Here are some recent publications with which I've been involved. Open Access articles are linked to the full text article, others are linked to their PubMed abstract. Technical papers on flow cytometry are bolded.
Maecker, H. T. 2009. Multiparameter flow cytometry monitoring of T cell responses. In Methods Mol Biol. 375-391. Link to PubMed asbstract
Butterfield, L. H., M. L. Disis, B. A. Fox, P. P. Lee, S. N. Khleif, M. Thurin, G. Trinchieri, E. Wang, J. Wigginton, D. Chaussabel, G. Coukos, M. Dhodapkar, L. Hakansson, S. Janetzki, T. O. Kleen, J. Kirkwood, C. Maccalli, H. Maecker, M. Maio, A. Malyguine, G. Masucci, A. K. Palucka, D. M. Potter, A. Ribas, L. Rivoltini, D. Schendel, B. Seliger, S. Selvan, C. L. Slingluff, Jr., D. F. Stroncek, H. Streicher, X. Wu, B. Zeskind, Y. Zhao, M. B. Zocca, H. Zwierzina, and F. M. Marincola. 2008. A systematic approach to biomarker discovery; Preamble to "the iSBTc-FDA taskforce on Immunotherapy Biomarkers". Journal of translational medicine 6:81. Link to full text
Nomura, L., V. C. Maino, and H. T. Maecker. 2008. Standardization and optimization of multiparameter intracellular cytokine staining. Cytometry A. Link to PubMed abstract
Chen, C. I., H. T. Maecker, and P. P. Lee. 2008. Development and dynamics of robust T-cell responses to CML under imatinib treatment. Blood 111:5342-5349. Link to PubMed abstract
Jacobson, M. A., Q. X. Tan, V. Girling, C. Poon, M. Van Natta, D. A. Jabs, M. Inokuma, H. T. Maecker, B. Bredt, and E. Sinclair. 2008. Poor predictive value of cytomegalovirus (CMV)-specific T cell assays for the development of CMV retinitis in patients with AIDS. Clin Infect Dis 46:458-466. Link to PubMed abstract
Janetzki, S., K. S. Panageas, L. Ben-Porat, J. Boyer, C. M. Britten, T. M. Clay, M. Kalos, H. T. Maecker, P. Romero, J. Yuan, W. Martin Kast, and A. Hoos. 2008. Results and harmonization guidelines from two large-scale international Elispot proficiency panels conducted by the Cancer Vaccine Consortium (CVC/SVI). Cancer Immunol Immunother 57:303-315. Link to PubMed abstract
Maecker, H. T. 2008. Measuring human cytokines. In Handbook of Human Immunology. A. Donnenberg, and M. O'Gorman, eds. CRC Press, Boca Raton, FL. 517-540. Link to CRC press description
Maecker, H. T., J. Hassler, J. K. Payne, A. Summers, K. Comatas, M. Ghanayem, M. A. Morse, T. M. Clay, H. K. Lyerly, S. Bhatia, S. A. Ghanekar, V. C. Maino, C. Delarosa, and M. L. Disis. 2008. Precision and linearity targets for validation of an IFNgamma ELISPOT, cytokine flow cytometry, and tetramer assay using CMV peptides. BMC Immunol 9:9. Link to full text
Siebert, J. C., M. Inokuma, D. M. Waid, N. D. Pennock, G. M. Vaitaitis, M. L. Disis, J. F. Dunne, D. H. Wagner, Jr., and H. T. Maecker. 2008. An analytical workflow for investigating cytokine profiles. Cytometry A 73:289-298. Link to PubMed abstract
Soares, A. P., T. J. Scriba, S. Joseph, R. Harbacheuski, R. A. Murray, S. J. Gelderbloem, A. Hawkridge, G. D. Hussey, H. Maecker, G. Kaplan, and W. A. Hanekom. 2008. Bacillus calmette-guerin vaccination of human newborns induces T cells with complex cytokine and phenotypic profiles. J Immunol 180:3569-3577. Link to PubMed abstract
Ghanekar, S. A., S. Bhatia, J. J. Ruitenberg, C. D. Rosa, M. L. Disis, V. C. Maino, H. T. Maecker, and C. A. Waters. 2007. Phenotype and in vitro function of mature MDDC generated from cryopreserved PBMC of cancer patients are equivalent to those from healthy donors. Journal of immune based therapies and vaccines 5:7. Link to full-text
Inokuma, M., C. dela Rosa, C. Schmitt, P. Haaland, J. Siebert, D. Petry, M. Tang, M. A. Suni, S. A. Ghanekar, D. Gladding, J. F. Dunne, V. C. Maino, M. L. Disis, and H. T. Maecker. 2007. Functional T cell responses to tumor antigens in breast cancer patients have a distinct phenotype and cytokine signature. J Immunol 179:2627-2633. Link to PubMed abstract
Streitz, M., L. Tesfa, V. Yildirim, A. Yahyazadeh, T. Ulrichs, R. Lenkei, A. Quassem, G. Liebetrau, L. Nomura, H. Maecker, H. D. Volk, and F. Kern. 2007. Loss of receptor on tuberculin-reactive T-cells marks active pulmonary tuberculosis. PLoS ONE 2:e735. Link to full-text
Sinclair, E., Q. X. Tan, M. Sharp, V. Girling, C. Poon, M. V. Natta, D. A. Jabs, M. Inokuma, H. T. Maecker, B. Bredt, and M. A. Jacobson. 2006. Protective immunity to cytomegalovirus (CMV) retinitis in AIDS is associated with CMV-specific T cells that express interferon- gamma and interleukin-2 and have a CD8+ cell early maturational phenotype. J Infect Dis 194:1537-1546. Link to PubMed abstract
Murray, R. A., N. Mansoor, R. Harbacheuski, J. Soler, V. Davids, A. Soares, A. Hawkridge, G. D. Hussey, H. Maecker, G. Kaplan, and W. A. Hanekom. 2006. Bacillus Calmette Guerin vaccination of human newborns induces a specific, functional CD8+ T cell response. J Immunol 177:5647-5651. Link to PubMed abstract
Nomura, L. E., B. Emu, R. Hoh, P. Haaland, S. G. Deeks, J. N. Martin, J. M. McCune, D. F. Nixon, and H. T. Maecker. 2006. IL-2 production correlates with effector cell differentiation in HIV-specific CD8+ T cells. AIDS Res Ther 3:18. Link to pdf
Maecker, H. T., and J. Trotter. 2006. Flow cytometry controls, instrument setup, and the determination of positivity. Cytometry A 69:1037. Link to PubMed abstract
Shu, S., A. J. Cochran, R. R. Huang, D. L. Morton, and H. T. Maecker. 2006. Immune responses in the draining lymph nodes against cancer: implications for immunotherapy. Cancer Metastasis Rev 25:233. Link to PubMed abstract
Disis, M. L., C. dela Rosa, V. Goodell, L. Y. Kuan, J. C. Chang, K. Kuus-Reichel, T. M. Clay, H. Kim Lyerly, S. Bhatia, S. A. Ghanekar, V. C. Maino, and H. T. Maecker. 2006. Maximizing the retention of antigen specific lymphocyte function after cryopreservation. J Immunol Methods 308:13. Link to PubMed abstract
Maecker, H. T., J. Moon, S. Bhatia, S. A. Ghanekar, V. C. Maino, J. K. Payne, K. Kuus-Reichel, J. C. Chang, A. Summers, T. M. Clay, M. A. Morse, H. K. Lyerly, C. Delarosa, D. P. Ankerst, and M. L. Disis. 2005. Impact of cryopreservation on tetramer, cytokine flow cytometry, and ELISPOT. BMC Immunol 6:17. Link to pdf
Maecker, H. T., A. Rinfret, P. D'Souza, J. Darden, E. Roig, C. Landry, P. Hayes, J. Birungi, O. Anzala, M. Garcia, A. Harari, I. Frank, R. Baydo, M. Baker, J. Holbrook, J. Ottinger, L. Lamoreaux, C. L. Epling, E. Sinclair, M. A. Suni, K. Punt, S. Calarota, S. El-Bahi, G. Alter, H. Maila, E. Kuta, J. Cox, C. Gray, M. Altfeld, N. Nougarede, J. Boyer, L. Tussey, T. Tobery, B. Bredt, M. Roederer, R. Koup, V. C. Maino, K. Weinhold, G. Pantaleo, J. Gilmour, H. Horton, and R. P. Sekaly. 2005. Standardization of cytokine flow cytometry assays. BMC Immunol 6:13. Link to pdf
Suni, M. A., V. C. Maino, and H. T. Maecker. 2005. Ex vivo analysis of T-cell function. Curr Opin Immunol 17:434. Link to PubMed abstract
Campbell, M. J., J. Scott, H. T. Maecker, J. W. Park, and L. J. Esserman. 2005. Immune dysfunction and micrometastases in women with breast cancer. Breast Cancer Res Treat 91:163. Link to PubMed abstract
Sun, Y., J. E. Schmitz, P. M. Acierno, S. Santra, R. A. Subbramanian, D. H. Barouch, D. A. Gorgone, M. A. Lifton, K. R. Beaudry, K. Manson, V. Philippon, L. Xu, H. T. Maecker, J. R. Mascola, D. Panicali, G. J. Nabel, and N. L. Letvin. 2005. Dysfunction of simian immunodeficiency virus/simian human immunodeficiency virus-induced IL-2 expression by central memory CD4+ T lymphocytes. J Immunol 174:4753. Link to PubMed abstract
Ghanekar, S. A., H. T. Maecker, and V. C. Maino. 2005. Immune monitoring using cytokine flow cytometry. In Manual of Clinical Laboratory Immunology. N. R. Rose, ed. ASM Press, Washington, DC. Link to ASM Press description
Maecker, H. T. 2005. The role of immune monitoring in evaluating cancer immunotherapy. In Immunotherapy of Cancer. M. L. Disis, ed. Humana Press, Totowa, NJ. Link to Humana Press description
Walker, J. M., H. T. Maecker, V. C. Maino, and L. J. Picker. 2004. Multicolor flow cytometric analysis in SIV-infected rhesus macaque. Methods Cell Biol 75:535. Link to PubMed abstract
Drohan, L., J. J. Harding, B. Holm, E. Cordoba-Tongson, C. L. Dekker, T. Holmes, H. Maecker, and E. D. Mellins. 2004. Selective developmental defects of cord blood antigen-presenting cell subsets. Hum Immunol 65:1356. Link to PubMed abstract
Maecker, H. T., T. Frey, L. E. Nomura, and J. Trotter. 2004. Selecting fluorochrome conjugates for maximum sensitivity. Cytometry A 62:169. Link to PubMed abstract
Maecker, H. T., and V. C. Maino. 2004. Analyzing T-cell responses to cytomegalovirus by cytokine flow cytometry. Hum Immunol 65:493. Link to PubMed abstract
Dunne, J. F., and H. T. Maecker. 2004. Automation of cytokine flow cytometry assays. J Assoc Lab Automation 9:5.
Maino, V. C., and H. T. Maecker. 2004. Cytokine flow cytometry: a multiparametric approach for assessing cellular immune responses to viral antigens. Clin Immunol 110:222. Link to PubMed abstract
Jacobson, M. A., H. T. Maecker, P. L. Orr, R. D'Amico, M. Van Natta, X. D. Li, R. B. Pollard, and B. M. Bredt. 2004. Results of a Cytomegalovirus (CMV)-Specific CD8+/Interferon- gamma + Cytokine Flow Cytometry Assay Correlate with Clinical Evidence of Protective Immunity in Patients with AIDS with CMV Retinitis. J Infect Dis 189:1362. Link to PubMed abstract
Ruitenberg, J. J., and C. A. Waters. 2003. A rapid flow cytometric method for the detection of intracellular cyclooxygenases in human whole blood monocytes and a COX-2 inducible human cell line. J Immunol Methods 274:93. Link to PubMed abstract
Maecker, H. T., and V. C. Maino. 2003. T cell immunity to HIV: defining parameters of protection. Current HIV Research 1:249. Link to PubMed abstract
Tu, W., S. Chen, M. Sharp, C. Dekker, A. M. Manganello, E. C. Tongson, H. T. Maecker, T. H. Holmes, Z. Wang, G. Kemble, S. Adler, A. Arvin, and D. B. Lewis. 2004. Persistent and selective deficiency of CD4+ T cell immunity to cytomegalovirus in immunocompetent young children. J Immunol 172:3260. Link to PubMed abstract
Maecker, H. T. 2004. Cytokine flow cytometry. In Flow Cytometry Protocols. T. S. Hawley, and R. G. Hawley, eds. Humana Press, Totowa, NJ, p. 95. Link to PubMed abstract
Walker, E. B., D. Haley, W. Miller, K. Floyd, K. P. Wisner, N. Sanjuan, H. T. Maecker, P. Romero, H. M. Hu, W. G. Alvord, J. W. Smith, B. A. Fox, and W. J. Urba. 2004. gp100(209-2M) peptide immunization of HLA-A2+ stage I-III melanoma patients induces significant increase in antigen-specific effector and long-term memory CD8+ T cells. Clin Cancer Res 10:668. Link to pdf
Deeks, S. G., J. N. Martin, E. Sinclair, J. Harris, T. B. Neilands, H. T. Maecker, E. Hagos, T. Wrin, C. J. Petropoulos, B. Bredt, and J. M. McCune. 2004. Strong cell-mediated immune responses are associated with the maintenance of low-level viremia in antiretroviral-treated individuals with drug-resistant human immunodeficiency virus type 1. J Infect Dis 189:312. Link to PubMed abstract
Dunne, J. F., and H. T. Maecker. 2004. Flow cytometry. In Principles of Immunopharmacology. F. P. Nijkamp, ed. Verlag, Basel. Link to publisher description
Shinn, A. H., N. C. Bravo, H. T. Maecker, and J. W. Smith. 2003. TNF-a detection using a flow cytometric assay to determine cellular responses to anthrax vaccine. J Immunol Methods 282:169. Link to PubMed abstract
Suni, M. A., H. S. Dunn, P. L. Orr, R. deLaat, E. Sinclair, S. A. Ghanekar, B. M. Bredt, J. F. Dunne, V. C. Maino, and H. T. Maecker. 2003. Performance of plate-based cytokine flow cytometry with automated data analysis. BMC Immunology 4:9. Link to pdf
Ghanekar, S. A., and H. T. Maecker. 2003. Cytokine flow cytometry: multiparametric approach to immune function analysis. Cytotherapy 5:1. Link to PubMed abstract
Nomura, L. E., E. D. DeHaro, L. N. Martin, and H. T. Maecker. 2003. Optimal preparation of rhesus macaque blood for cytokine flow cytometric analysis. Cytometry 53A:28. Link to PubMed abstract
Smith, J. W., 2nd, E. B. Walker, B. A. Fox, D. Haley, K. P. Wisner, T. Doran, B. Fisher, L. Justice, W. Wood, J. Vetto, H. Maecker, A. Dols, S. Meijer, H. M. Hu, P. Romero, W. G. Alvord, and W. J. Urba. 2003. Adjuvant immunization of HLA-A2-positive melanoma patients with a modified gp100 peptide induces peptide-specific CD8+ T-cell responses. J Clin Oncol 21:1562. Link to PubMed abstract
He, X. S., K. Mahmood, H. T. Maecker, T. H. Holmes, G. W. Kemble, A. M. Arvin, and H. B. Greenberg. 2003. Analysis of the frequencies and of the memory T cell phenotypes of human CD8+ T cells specific for influenza A viruses. J Infect Dis 187:1075. Link to PubMed abstract
Maecker, H. T. 2003. Human CD81 Directly Enhances TH1 and TH2 Cell Activation, but Preferentially Induces Proliferation of TH2 Cells upon Long-Term Stimulation. BMC Immunol 4:1. Link to pdf
Maecker, H. L., Z. Yun, H. T. Maecker, and A. J. Giaccia. 2002. Epigenetic changes in tumor Fas levels determine immune escape and response to therapy. Cancer Cell 2:139. Link to PubMed abstract
Dunn, H. S., D. J. Haney, S. A. Ghanekar, P. Stepick-Biek, D. B. Lewis, and H. T. Maecker. 2002. Dynamics of CD4 and CD8 T cell responses to cytomegalovirus in healthy human donors. J Infect Dis 186:15. Link to PubMed abstract
Maino, V. C., H. T. Maecker, and L. J. Picker. 2002. Antigen-specific cytokine responses in HIV disease. In Cellular Aspects of HIV Infection. A. Cossarizza, and D. Kaplan, eds. Wiley-Liss, New York, p. 371.
Suni, M. A., S. A. Ghanekar, D. W. Houck, H. T. Maecker, S. B. Wormsley, L. J. Picker, R. B. Moss, and V. C. Maino. 2001. CD4(+)CD8(dim) T lymphocytes exhibit enhanced cytokine expression, proliferation and cytotoxic activity in response to HCMV and HIV-1 antigens. Eur J Immunol 31:2512. Link to PubMed abstract
Maecker, H. T., H. S. Dunn, M. A. Suni, E. Khatamzas, C. J. Pitcher, T. Bunde, N. Persaud, W. Trigona, T. M. Fu, E. Sinclair, B. M. Bredt, J. M. McCune, V. C. Maino, F. Kern, and L. J. Picker. 2001. Use of overlapping peptide mixtures as antigens for cytokine flow cytometry. J Immunol Methods 255:27. Link to PubMed abstract
Maecker, H. T., S. A. Ghanekar, M. A. Suni, X. S. He, L. J. Picker, and V. C. Maino. 2001. Factors affecting the efficiency of CD8+ T cell cross-priming with exogenous antigens. J Immunol 166:7268. Link to pdf
Ghanekar, S. A., L. E. Nomura, M. A. Suni, L. J. Picker, H. T. Maecker, and V. C. Maino. 2001. Gamma interferon expression in CD8(+) T cells is a marker for circulating cytotoxic T lymphocytes that recognize an HLA A2-restricted epitope of human cytomegalovirus phosphoprotein pp65. Clin Diagn Lab Immunol 8:628. Link to pdf
Maecker, H. T., S. Auffermann-Gretzinger, L. E. Nomura, A. Liso, D. K. Czerwinski, and R. Levy. 2001. Detection of CD4 T-cell responses to a tumor vaccine by cytokine flow cytometry. Clin Cancer Res 7:902s. Link to PubMed abstract
He, X. S., B. Rehermann, J. Boisvert, J. Mumm, H. T. Maecker, M. Roederer, T. L. Wright, V. C. Maino, M. M. Davis, and H. B. Greenberg. 2001. Direct functional analysis of epitope-specific CD8+ T cells in peripheral blood. Viral Immunol 14:59. Link to PubMed abstract
Maecker, H. T., V. C. Maino, and L. J. Picker. 2000. Immunofluorescence analysis of T-cell responses in health and disease. J Clin Immunol 20:391. Link to PubMed abstract
Nomura, L. E., J. M. Walker, and H. T. Maecker. 2000. Optimization of whole blood antigen-specific cytokine assays for CD4(+) T cells. Cytometry 40:60. Link to PubMed abstract
Asanuma, H., M. Sharp, H. T. Maecker, V. C. Maino, and A. M. Arvin. 2000. Frequencies of memory T cells specific for varicella-zoster virus, herpes simplex virus, and cytomegalovirus by intracellular detection of cytokine expression. J Infect Dis 181:859. Link to PubMed abstract